So nothing is tweaked. As I have stated before. We can use a duo 2 along with two ultra studios with no problems. No video hiccups, audio plays out fine. I have recently tried just playing video out with OBS studio using the decklink play out in several instances and it plays out fine via the Quad 2 on the Mac Pro. This topic has been open for over 4 days so I have tried many things to try to isolate the issue. Me testing with OBS play out tells me that it’s not a hardware issue that is limiting me from being able to play out videos via the card. Someone stated earlier that trying a different codec could help. I tried the suggested codecs and no luck. I tried the videos that come with some installations and those videos also do not play out correctly. I just need to know what I need to adjust in CasparCG so that it just works via the Quad 2. If not I am perfectly ok with using an ultra studio hd mini which works while using the Quad 2 for video playback.