Stay away from Adobe FMLE for starters! It’s too old to be considered worth using (mainly due to old Mainconcept H.264 codecs). For transcoding you can use AWS Elemental MediaLive or do it in house (which in case of a 24/7 channel might be cheaper) with ffmpeg.
Check if OBS fit your encoding and switching needs - for some scenarios it’s worth consideridering it as a Caspar replacement (i.e. when you have inputs that are far from professional, clips with varying frame rate, etc.). You won’t have playlist control out of the box but it’s scriptable (LUA), it’s got partial remote control (websockets), it has good working RTMP output out of the box. I know that it’s able to run for a year without the need to restart if you’re not poking it too much (https://twitter.com/przemyslawpluta/status/962451387144646657).